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Adverse Reaction - Definition of Adverse Reaction

By Lynne Eldridge MD, About.com

Updated October 21, 2008

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

Definition:

An unwanted or unexpected negative reaction to a medication or treatment that is used in an approved manner.

Adverse reactions can be mild, such as a simple rash, or severe and life-threatening in nature. They can occur immediately when a treatment is started, or develop over time. Some adverse reactions are common, and can be anticipated by your doctor, whereas others occur very rarely.

Examples:
Evelyn developed hives when she began the new medication to help with her lung cancer. Her oncologist told her this was an adverse reaction that some people have, and recommended a different medication.
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